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PRP Mesotherapy: Vampire Facial

This document has been prepared to help provide you with information about PRP Therapy of the skin, or as it is called at NoviSkin – Vampire Facial – its risks, and alternative treatments. It is important that you read this information carefully and completely.


Skin Rejuvenation through Mesotherapy. An article written by Dr Minoka Nadesan.

Link to the article.


Platelet rich plasma (PRP) is the cell free plasma containing a higher than normal concentration of human platelets per volume. Treatment with PRP has become an increasing clinical tool used for tissue argumentation and bone regeneration. This includes:

  • Facial rejuvenation therapy for wrinkles and solar damage skin
  • Surgery – free repair of sports injuries
  • Cutaneous wound healing

PRP therapy is a treatment option if you are presenting with any of these indications:

  • Reduction of down time after invasive aesthetic procedures
  • Sun damage
  • Scarring
  • Burn wounds
  • Pigmentation
  • Fine lines and wrinkles
  • Dehydrated skin
  • Radiance optimizing
  • Areas treatable: Face, neck décolletage area

Explanation /Procedure

Step 1: Blood collection
As your own (autologous) blood is used, it is first collected by venesection, the same procedure used in blood tests or blood donations. The site of the venesection is usually a large vein in your elbow. Up to 20ml of blood may be collected.

Step 2: Centrifuge
The blood will then be spun down in a centrifuge to separate the components. The process takes 15 minutes. The platelet rich plasma (PRP) is then harvested and there are a variety of different ways this can be done with a CelluVance™ kit. Anti aging therapies require between 2-8ml of PRP which will then be extracted from the centrifuged blood.

Step 3: Injection
Involves injecting the prepared solution into the different layers of the skin using different injecting technique namely:

  • Superficial nappage - superficial injections to the epidermal layer = 1mm depth.
  • Superficial intradermal- Multiple papules 2mm, made to the intrabasal layer.
  • Deep intra dermal - Point by Point injections = 4 - 10 mm depth

Mechanism of action

When the concentrated platelets in the PRP are activated, it mimics the wound-healing cascade and accelerates recovery by releasing a variety of cytokines and growth factors. This results in new formation of extracellular proteins such as collagen. In practice treatment with PRP is made possible by easily obtaining autologous PRP with the aid of commercial kits.

The CelluVance™ kits uses the patient’s own blood to stimulate the collagen production ensuring that is no risk of contamination with any transmissible diseases. The kit concentrates platelets via a centrifugal step in special CE tubes followed by a safe and effective thrombin free activation method.

Post Care Instructions

Patient can experience some redness, which should resolve within 24 hours. There is no down time and patients can continue with normal skin care regime after 48 hours. The remaining clear blood extract is used to sterilize the treated area and no post care cream is needed. This will immediately reduce swelling and redness. Bruising is common if delicate or sensitive areas are to be treated but this will resolve within 7 – 10 days. Scabs from wound healing should not be picked or removed, as it can result in pigmentation or scarring. If patient experiences any side effects other than above mentioned, they should contact NoviSkin immediately.

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